Semax (Nootropic Peptide)
Semax is a synthetic peptide derived from a fragment of adrenocorticotropic hormone (ACTH). It has primarily been investigated for its neuroprotective properties and effects on brain function, including attention, memory and cognitive performance.
Potential Benefits
- Cognitive Function: Investigated for potential effects on attention, memory and information processing.
- Neuroprotection: Studied for its potential to protect nerve cells from damage.
- Neuroplasticity: Research suggests it may influence pathways involved in neuronal growth and adaptation.
- Brain Recovery: Investigated in Russia for potential applications in recovery following ischaemic stroke.
- BDNF Activity: Preclinical research suggests it may influence brain-derived neurotrophic factor (BDNF), a protein involved in neuronal health.
Possible Side Effects
- Headache or Irritation: Headache and local irritation are potential concerns, particularly with nasal preparations.
- Neurological Effects: Changes in brain electrical activity have been reported in limited clinical literature.





