Quetiapine is an atypical antipsychotic used primarily for schizophrenia and bipolar disorder, with certain formulations also used alongside antidepressants for major depressive disorder. It affects dopamine and serotonin signalling in the brain.

Benefits:

• Helps manage psychotic symptoms
• Helps stabilise mood in bipolar disorder
• Treats manic episodes
• Can be used as adjunctive treatment for depression
• Has significant sedative properties

Off-Label Uses:

• Insomnia
• Anxiety disorders in selected clinical settings
• Other behavioural or mood disorders under specialist supervision

Potential Side Effects:

• Drowsiness and fatigue
• Increased blood glucose and cholesterol
• Dizziness and low blood pressure

Common Use: Dosing depends on the condition and formulation. Treatment is generally started at a low dose and increased gradually when clinically appropriate.

Note: Quetiapine should not routinely be used solely as a sleeping tablet without medical assessment due to its metabolic, cardiovascular and neurological risks.