Raloxifene is a selective estrogen receptor modulator (SERM) that blocks estrogen effects in some tissues while preserving beneficial effects in others. Among anabolic steroid users, it is sometimes used for estrogen-related complications.
Benefits for steroid users:
Helps prevent or reduce gynecomastia by blocking estrogen receptors in breast tissue
Useful when estrogen-related symptoms persist despite aromatase inhibitor use
Does not suppress testosterone production, unlike some hormonal therapies
May help counter estrogen-driven fat and water retention effects indirectly
Provides bone-protective effects, which can be beneficial during post-cycle recovery
Main side effects:
Hot flashes
Leg cramps
Increased risk of blood clots
Raloxifene does not lower estrogen levels; it blocks estrogen’s action in specific tissues, making it a targeted option for managing estrogenic side effects.