Hydroxyzine hydrochloride is a first-generation antihistamine with sedative and anxiolytic properties. It is used for itching and allergic conditions and can also be prescribed for short-term management of anxiety.

Benefits:

• Relieves itching and allergic skin symptoms
• Reduces hives (urticaria)
• Can provide short-term relief of anxiety
• Produces a calming and sedating effect
• May help with sleep when anxiety or itching is contributing to insomnia

Off-Label Uses:

• Short-term insomnia
• Anxiety-related sleep disturbance
• Nausea in selected clinical situations
• Adjunctive treatment for certain withdrawal-related symptoms

Potential Side Effects:

• Drowsiness and fatigue
• Dizziness
• Dry mouth

Common Use: Dosing depends on the indication and formulation. When used for anxiety or itching, it may be taken several times daily; for its sedating effects, it is often taken in the evening.

Note: Hydroxyzine can significantly impair alertness. Avoid alcohol and use caution with opioids, benzodiazepines and other sedating medicines. It may not be suitable for people with certain heart-rhythm problems.